Case Report


Micropapillary carcinoma of the breast: A case report and review of the literature

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1 Gynaecology Department, Ibn Rochd University Hospital, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco

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Sabiri Rachida

Gynaecology Department, Ibn Rochd University Hospital, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca,

Morocco

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Article ID: 100037G06SR2024

doi: 10.5348/100037G06SR2024CR

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How to cite this article

Rachida S, Cherkaoui A, Benhaddougua K, Zine M, Houssine B, Sakher M, Naima S. Micropapillary carcinoma of the breast: A case report and review of the literature. Edorium J Gynecol Obstet 2024;9(2):1– 4.

ABSTRACT


Introduction: A rare entity accounting for less than 3% of all breast carcinomas. Its prognosis is poor due to the presence of vascular emboli and lymph node metastases. However, the micropapillary appearance is not an independent prognostic factor.

Case Report: We report the case of a 38-year-old female patient who presented with a mass of the left breast, the anatomopathology of which was in favor of an invasive micropapillary carcinoma (IMPC). The clinical and radiological presentations are characteristically non-specific: nests of tumor cells with irregular peripheral borders separated from the fibrocollagenous stroma by a clear space. There is no conjunctivo-vascular axis in the middle of the tumor cells. The mitotic index is generally high.

Conclusion: This type of carcinoma is characterised by an aggressive evolution and unfavourable prognosis, frequent alterations of chromosome 8 and a luminal B phenotype, and histologically.

Keywords: Breast, Micropapillary carcinoma, Rare entity

SUPPORTING INFORMATION


Author Contributions

Sabiri Rachida - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

A Cherkaoui - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

K Benhaddougua - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

M Zine - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Boufettal Houssine - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Mahdaoui Sakher - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Samouh Naima - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Guaranter of Submission

The corresponding author is the guarantor of submission.

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Consent Statement

Written informed consent was obtained from the patient for publication of this article.

Data Availability

All relevant data are within the paper and its Supporting Information files.

Conflict of Interest

Authors declare no conflict of interest.

Copyright

© 2024 Sabiri Rachida et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.