Case Report
1 Gynecologic Department, Centre Hospitalier Universitaire Ibn Rochd, Faculté de Médecine et Pharmacie, Université Hassan II de Casablanca, Casablanca, Morocco
Address correspondence to:
Hlaibi Omnia
Centre Hospitalier Universitaire Ibn Rochd, Faculté de Médecine et Pharmacie, Université Hassan II de Casablanca, Casablanca,
Morocco
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Article ID: 100031G06FI2023
Introduction: Sister Mary Joseph nodule is an eponymous term for a malignant metastatic umbilical nodule. It is a rare but important physical finding because it is indicative of advanced malignancy. The primary tumor is usually an adenocarcinoma, rarely a squamous cell carcinoma, melanoma, or sarcoma.
Case Report: We report the clinical case of a 64-year-old woman with metastatic ovarian adenocarcinoma and umbilical cutaneous metastasis. The diagnosis was established upon the umbilical node biopsy in April 2020, after the patient presented with an abdominal distension and respiratory difficulties.
Conclusion: Umbilical skin metastases are rare, and they are associated with advanced metastatic disease and a very poor prognosis. Through this work we try to clarify the mechanisms and the prognosis of this rare manifestation, and put the point on the importance of an early diagnosis.
Keywords: Ovarian adenocarcinoma, Sister Mary Joseph nodule, Umbilical metastasis
Faizi Issam - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Final approval of the version to be published
Sami Zineb - Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Hlaibi Omnia - Acquisition of data, Analysis of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Boufettal Houssin - Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Mahdaoui Sakher - Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Samouh Naima - Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2023 Faizi Issam et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.