Case Series


Outcomes of pregnancy in patients with Hodgkin lymphoma

,  ,  ,  

1 Haematology Unit, Medical Department, Hospital Tengku Ampuan Afzan, Kuantan, Malaysia

2 Maternal Fetal Medicine Unit, Obstetrics & Gynaecology Department, Hospital Tengku Ampuan Afzan, Kuantan, Malaysia

3 Pathology Department, Hospital Tengku Ampuan Afzan, Kuantan, Malaysia

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Sopian Abdul Wahab

Haematology Unit, Hospital Tengku Ampuan Afzan, Jalan Tanah Putih, 25100, Kuantan,

Malaysia

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Article ID: 100025G06SW2022

doi: 10.5348/100025G06SW2022CS

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How to cite this article

Wahab SA, Husin R, Salleh H, Kori AN. Outcomes of pregnancy in patients with Hodgkin lymphoma. Edorium J Gynecol Obstet 2022;7:100025G06SW2022.

ABSTRACT


Introduction: Hodgkin lymphoma (HL) is a common lymphoma that occurs in young age group. Thus, the occurrence of HL is inevitable. However, as the disease implies, there is no single study to prove the safety use of chemotherapy in pregnancy.

Case Series: As for our center, in 2019 we encountered three patients with diagnosis of HL which was diagnosed at 16 weeks, 30 weeks, and 32 weeks of gestation. The outcome of the pregnancy was 1 death due to severe prematurity, and two live births. The details of patient presentation, histology, imaging for staging, progress and outcome of pregnancy were reviewed via the patient’s medical record.

Conclusion: The outcomes of pregnancies may varies depending on the timing of the diagnosis and the exposure of chemotherapy in the stage of pregnancy.

Keywords: Chemotherapy, Hodgkin lymphoma, Pregnancy, Prematurity

SUPPORTING INFORMATION


Acknowledgments

I would like to acknowledge Dr. Norra Harun, pathologist in Hospital Tengku Ampuan Afzan, Kuantan and Dr. Kim Kwan Tan, pathologist from Hospital Pakar Sultanah Fatimah, Muar for their contributions in providing the images for the above patients.

Author Contributions

Sopian Abdul Wahab - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Final approval of the version to be published

Roziah Husin - Interpretation of data, Drafting the article, Final approval of the version to be published

Hafliza Salleh - Interpretation of data, Drafting the article, Final approval of the version to be published

Ahlam Naila Kori - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published

Guaranter of Submission

The corresponding author is the guarantor of submission.

Source of Support

None

Consent Statement

Written informed consent was obtained from the patient for publication of this article.

Data Availability

All relevant data are within the paper and its Supporting Information files.

Conflict of Interest

Authors declare no conflict of interest.

Copyright

© 2022 Sopian Abdul Wahab et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.